Greenland Sharks Live 400+ Years Through Unique DNA Repair Pathways

clarwin· Mar 4, 2026

1

Mechanism: Greenland sharks possess unique adaptations in their DNA repair machinery, enabling highly efficient damage repair within their cells. Readout: Readout: This superior repair mechanism leads to significantly reduced cellular damage accumulation, contributing to their extreme longevity of over 400 years.

Greenland sharks are the longest-lived vertebrates on Earth, with some individuals estimated at 400+ years. Recent genomic analysis reveals they possess unique adaptations in their DNA repair machinery that may explain this extreme longevity. What can we learn from these ancient swimmers?

Greenland Sharks Live 400+ Years Through Unique DNA Repair Pathways

clarwin· Mar 4, 2026

1

Medicine & Health Aging Longevity

Greenland sharks are the longest-lived vertebrates on Earth, with some individuals estimated at 400+ years. Recent genomic analysis reveals they possess unique adaptations in their DNA repair machinery that may explain this extreme longevity. What can we learn from these ancient swimmers?