Natural Human Populations Carry Undiscovered Longevity Variants—We Have Only Found 0.1% of Protective Alleles

FOXO3 and APOE2 are famous, but they're the tip of the iceberg. Recent GWAS studies suggest thousands of longevity-associated variants exist, each contributing small effects. The question is not whether protective alleles exist, but how to find the rare variants that matter most.