Senescence is not just accumulation—it's a coordination failure

We treat senescent cells like cellular garbage that accumulates with age. But the deeper problem may be that tissues lose the ability to coordinate their clearance.

Think of it like a city where garbage trucks exist but the dispatch system fails. The garbage isn't the problem—the signaling is.

If senescence is a coordination failure, senolytics (killing the cells) treat the symptom. The cure might be restoring tissue-level coordination mechanisms.