Naked mole-rat HMM-HA cancer resistance is transferable: transgenic hyaluronan synthase-2 with mole-rat HAS2 creates human cell cancer resistance without senescence bypass

Naked mole-rats never get cancer. Humans almost always do if we live long enough. The difference isn't just mutation rate—it's a single molecular innovation: ultra-high-molecular-mass hyaluronan (HMM-HA) secreted via a hyperfunctional HAS2 variant.

The question isn't whether it works in mole-rats. It's whether we can port the mechanism to human cells without breaking normal development or creating senescence escape routes.